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Blood vessels guide immune cells to metastases

07/20/2026 | by Koh
It has long been suspected that endothelial cells, the specialized cells lining the inner walls of blood vessels, play a key role in determining how the body’s immune system responds to tumors. Researchers at the German Cancer Research Center (DKFZ) in Heidelberg and the Medical Faculty Mannheim of Heidelberg University have now identified, in mouse studies, a specialized population of blood vessel lining endothelial cells that enable an effective immune defense against cancer metastases in the liver. The findings could pave the way for novel combination therapies for cancer.

Read more at dkfz.de

Prevention: Explore, Understand, Apply

07/16/2026 |

Science Fair hosted by the Kompetenznetzwerk Präventivmedizin aboard the MS Wissenschaft on July 25 in Heidelberg.

Staying healthy and preventing disease are the focus of a Science Fair aboard the MS Wissenschaft on Saturday, July 25. The Kompetenznetzwerk Präventivmedizin Baden-Württemberg, in cooperation with AOK and other partners, invites visitors to explore current research and innovations in disease prevention.

Read more at umm.de

Brain tumor vaccine shows promising long-term results

07/03/2026 | by Koh

A novel vaccine strategy for certain malignant brain tumors has the potential to fundamentally improve treatment for patients. Researchers from the German Cancer Research Center (DKFZ), University Medicine Mannheim, Heidelberg University Hospital, and numerous partner institutions* have reported encouraging long-term results from a clinical trial of a vaccine designed to activate the immune system against a common genetic mutation found in these tumors.

Read more at dkfz.de

How Tumors Evade Immunotherapy - and How to Prevent It

07/02/2026 | by Koh

Researchers at the German Cancer Research Center (DKFZ) have identified a previously unknown key mechanism by which cancer cells suppress the immune system and thus evade the effects of immunotherapies. At the same time, the new study in mouse models and human tumor samples points to a promising way to prevent resistance to immunotherapy.

Read more at dkfz.de

11/09/2025
» Ângela Gonçalves' talk at the Falling Walls Summit in Berlin
Ângela Gonçalves’ talk at the Falling Walls Summit in Berlin
Prof. Dr. Ângela Gonçalves (Breakthrough of the Year Award 2025) gave a talk at the Falling Walls Summit in November 2025.

News Archiv

07/01/2026
» Newly Discovered Marker for Metastatic Colorectal Cancer Is the Achilles’ Heel of Highly Aggressive Tumor Cells

07/01/2026
» Shalini Saxena new Interim Administrative Director

06/30/2026
» Double ERC success for DKFZ researchers

06/30/2026
» Brain tumor resists high-dose radiation therapy

06/03/2026
» Fat hack protects against cell death

05/27/2026
» World No Tobacco Day 2026: Clear majority supports standardized packaging for tobacco products and e-cigarettes

05/12/2026
» How immune cells influence Alzheimer’s disease: T cells move into the focus of research

05/11/2026
» What really helps people quit smoking

05/07/2026
» Leukemia stem cells cause treatments to fail - Findings open new avenues to overcome resistance

04/10/2026
» Molecular analyses could improve treatment prospects for a rare soft tissue tumor

04/08/2026
» Strong public support for tobacco tax increases and a prevention levy

03/12/2026
» New research project on radiation-induced sarcomas coordinated from Mannheim

02/20/2026
» Feb 28 – Rare Disease Day: New Information Pages on Radiation-Induced Sarcomas

01/27/2026
» Double ERC success for DKFZ researchers

01/26/2026
» AI learns from animals: New approach to improve surgical imaging

01/21/2026
» In Memoriam: Professor Dr. med. Dr. h.c. Klaus van Ackern

01/12/2026
» Alliance of the Heidelberg and Mannheim University Hospitals Launched

12/18/2025
» FLAURARE Study Launches

12/04/2025
» New Public Health Index: Germany Ranks Second-to-Last in Implementing Evidence-Based Prevention Measures

11/28/2025
» Lautenschläger Prize for Young Scientists 2025 awarded to Lukas Bunse

11/20/2025
» Research Award for Jens Puschhof: How Bacteria Can Trigger Cancer

11/14/2025
» Three “Highly Cited Researchers” at the Medical Faculty Mannheim

11/13/2025
» Ten DKFZ Researchers Among the World’s Top 1% Most-Cited in 2025

11/07/2025
» How the Biological Clock Ticks in the Female Reproductive Tract – Breakthrough of the Year Award 2025 for Ângela Gonçalves

10/27/2025
» Role of intestinal bacteria in the development of colorectal cancer: Emmy Noether grant for DKFZ researcher Jens Puschhof

10/14/2025
» Prestigious DFG funding for DKFZ projects

09/26/2025
» Mannheim to lead new DFG research unit

08/14/2025
» Freezing brain tumor cells in a dormant state

07/15/2025
» ERC funding for research into improved cancer immunotherapies

05/27/2025
» Third German Award for Research in Cancer Prevention honors outstanding scientists

05/26/2025
» Explainable artificial intelligence increases the accuracy and endurance of dermatologists in melanoma diagnosis

03/17/2025
» New approach for T-cell immunotherapy against malignant brain tumors

02/27/2025
» DKFZ Hector Cancer Institute at University Medicine Mannheim receives further substantial funding from the Hector Foundation

02/11/2025
» New perspectives for personalized therapy of brain tumors

10/17/2024
» Takeda Oncology Research Award 2024: DKFZ scientists recognized for outstanding research

08/11/2024
» New vaccines offer hope for brain tumor patients

06/28/2024
» German Cancer Research Center kicks off important expansion project

06/14/2024
» DKFZ Hector Cancer Institute rated outstanding in international evaluation

05/28/2024
» With mirrored RNA against highly aggressive brain tumors

05/08/2024
» Circulating tumor cells provide detailed insights into cancer heterogeneity

05/03/2024
» Newly discovered mechanism of T cell control can interfere with cancer immunotherapies

04/15/2024
» Paul Martini Award for therapeutic vaccines against brain tumors

04/11/2024
» ERC Advanced Grants for Hannah Monyer and Michael Platten

03/14/2024
» Machine learning classifier accelerates the development of cellular immunotherapies

09/27/2023
» Transgenic T cells agains malignant brain tumors

09/22/2023
» Life Sciences Bridge Award für Lukas Bunse

09/21/2023
» Mutation-specific peptide vaccine against midline gliomas used in patients for the first time

01/24/2023
» What keeps the immune defense in brain tumors functional

12/20/2022
» Enzyme inhibition promotes bone formation and curbs the development of bone metastases (dkfz.de)

10/24/2022
» How tumors suppress the development of metastases (dkfz.de)

01/20/2022
» DKFZ-Hector Cancer Institute at the University Medical Centre Mannheim (dkfz.de)

03/17/2022
» Wer profitiert von einer zielgerichteten Therapie beim nicht-kleinzelligen Lungenkarzinom? (dkfz.de)

06/13/2022
» Vom Bild zum Gen: Was Minitumoren über zukünftige Therapiemöglichkeiten bei Darmkrebs verraten (dkfz.de)

02/01/2021
» Resistenz gegenüber Krebsimmuntherapien überwinden (dkfz.de)

07/31/2019
» Founding ceremony of the DKFZ-Hector Cancer Institute at the University Medical Center Mannheim (dkfz.de)