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How immune cells influence Alzheimer’s disease: T cells move into the focus of research

05/12/2026 | 
Specific T cells react selectively to amyloid deposits in the brain and may drive inflammatory processes in Alzheimer’s disease. The findings, obtained in mice with an Alzheimer’s-like condition, open up potential new approaches for precisely timed therapies. This was demonstrated by researchers at the German Cancer Research Center (DKFZ) and the Mannheim Medical Faculty of Heidelberg University.

Read more at dkfz.de

What Really Helps People Quit Smoking

05/11/2026 | by Koh

Whether people try to quit smoking depends heavily on public health policies in their respective countries – whether they are successful, however, depends primarily on their personal environment and behavior. This was the finding of researchers from the German Cancer Research Center (DKFZ) in an international study.

Read more at dkfz.de

Leukemia stem cells cause treatments to fail - Findings open new avenues to overcome resistance

05/07/2026 | by Koh

Scientists from the German Cancer Research Center (DKFZ) and the HI-STEM* Stem Cell Institute have deciphered a key mechanism that contributes to treatment failure in acute myeloid leukemia (AML). They show that there are not just one, but four different subtypes of leukemia stem cells. This diversity could explain why one of the most important AML drugs does not work sufficiently in some patients or loses its effectiveness over time - resulting in the return of leukemia. This discovery lays an important foundation for more precise and long-term successful treatment strategies that could specifically overcome resistance mechanisms.

Read more at dkfz.de

Molecular analyses could improve treatment prospects for a rare soft tissue tumor

04/10/2026 | by Koh

Desmoplastic small round cell tumor is a rare, aggressive, and difficult-to-treat soft tissue cancer. Researchers at the National Center for Tumor Diseases (NCT) Heidelberg and the German Cancer Research Center (DKFZ) conducted comprehensive analyses of 30 tumors and identified potential personalized treatment options for nearly all patients. In individual cases, novel targeted approaches were able to halt disease progression for a surprisingly long period of time.

Read more at dkfz.de

11/09/2025
» Ângela Gonçalves' talk at the Falling Walls Summit in Berlin
Ângela Gonçalves’ talk at the Falling Walls Summit in Berlin
Prof. Dr. Ângela Gonçalves (Breakthrough of the Year Award 2025) gave a talk at the Falling Walls Summit in November 2025.

News Archiv

04/08/2026
» Strong public support for tobacco tax increases and a prevention levy

03/12/2026
» New research project on radiation-induced sarcomas coordinated from Mannheim

02/20/2026
» Feb 28 – Rare Disease Day: New Information Pages on Radiation-Induced Sarcomas

01/27/2026
» Double ERC success for DKFZ researchers

01/26/2026
» AI learns from animals: New approach to improve surgical imaging

01/21/2026
» In Memoriam: Professor Dr. med. Dr. h.c. Klaus van Ackern

01/12/2026
» Alliance of the Heidelberg and Mannheim University Hospitals Launched

12/18/2025
» FLAURARE Study Launches

12/04/2025
» New Public Health Index: Germany Ranks Second-to-Last in Implementing Evidence-Based Prevention Measures

11/28/2025
» Lautenschläger Prize for Young Scientists 2025 awarded to Lukas Bunse

11/20/2025
» Research Award for Jens Puschhof: How Bacteria Can Trigger Cancer

11/14/2025
» Three “Highly Cited Researchers” at the Medical Faculty Mannheim

11/13/2025
» Ten DKFZ Researchers Among the World’s Top 1% Most-Cited in 2025

11/07/2025
» How the Biological Clock Ticks in the Female Reproductive Tract – Breakthrough of the Year Award 2025 for Ângela Gonçalves

10/27/2025
» Role of intestinal bacteria in the development of colorectal cancer: Emmy Noether grant for DKFZ researcher Jens Puschhof

10/14/2025
» Prestigious DFG funding for DKFZ projects

09/26/2025
» Mannheim to lead new DFG research unit

08/14/2025
» Freezing brain tumor cells in a dormant state

07/15/2025
» ERC funding for research into improved cancer immunotherapies

05/27/2025
» Third German Award for Research in Cancer Prevention honors outstanding scientists

05/26/2025
» Explainable artificial intelligence increases the accuracy and endurance of dermatologists in melanoma diagnosis

03/17/2025
» New approach for T-cell immunotherapy against malignant brain tumors

02/27/2025
» DKFZ Hector Cancer Institute at University Medicine Mannheim receives further substantial funding from the Hector Foundation

02/11/2025
» New perspectives for personalized therapy of brain tumors

10/17/2024
» Takeda Oncology Research Award 2024: DKFZ scientists recognized for outstanding research

08/11/2024
» New vaccines offer hope for brain tumor patients

06/28/2024
» German Cancer Research Center kicks off important expansion project

06/14/2024
» DKFZ Hector Cancer Institute rated outstanding in international evaluation

05/28/2024
» With mirrored RNA against highly aggressive brain tumors

05/08/2024
» Circulating tumor cells provide detailed insights into cancer heterogeneity

05/03/2024
» Newly discovered mechanism of T cell control can interfere with cancer immunotherapies

04/15/2024
» Paul Martini Award for therapeutic vaccines against brain tumors

04/11/2024
» ERC Advanced Grants for Hannah Monyer and Michael Platten

03/14/2024
» Machine learning classifier accelerates the development of cellular immunotherapies

09/27/2023
» Transgenic T cells agains malignant brain tumors

09/22/2023
» Life Sciences Bridge Award für Lukas Bunse

09/21/2023
» Mutation-specific peptide vaccine against midline gliomas used in patients for the first time

01/24/2023
» What keeps the immune defense in brain tumors functional

12/20/2022
» Enzyme inhibition promotes bone formation and curbs the development of bone metastases (dkfz.de)

10/24/2022
» How tumors suppress the development of metastases (dkfz.de)

01/20/2022
» DKFZ-Hector Cancer Institute at the University Medical Centre Mannheim (dkfz.de)

03/17/2022
» Wer profitiert von einer zielgerichteten Therapie beim nicht-kleinzelligen Lungenkarzinom? (dkfz.de)

06/13/2022
» Vom Bild zum Gen: Was Minitumoren über zukünftige Therapiemöglichkeiten bei Darmkrebs verraten (dkfz.de)

02/01/2021
» Resistenz gegenüber Krebsimmuntherapien überwinden (dkfz.de)

07/31/2019
» Founding ceremony of the DKFZ-Hector Cancer Institute at the University Medical Center Mannheim (dkfz.de)